Photo courtesy of Dr Andrew Dwyer, Boston College, USA.
The main symptom of Kallmann syndrome / CHH is a failure to start or fully complete puberty.
However there are a range of additional symptoms that may or may not be present in any individual case.
KS / CHH can be seen as a broad spectrum condition with each case having different symptoms and different symptoms that occur along side the failure to go through puberty.
Lack of sense of smell is the defining symptom of Kallmann syndrome as it is found in 100% of cases, but is not present in CHH.
Other symptoms may only appear depending on the precise genetic cause of each condition.
Siblings, even twins, with KS / CHH may have different symptoms and severity of symptoms.